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Cynomolgus ERBB2 / HER2 / CD340 HEK293 Cell Line 猴ERBB2 / HER2 / CD340 HEK293过表达细胞系
靶点信息

Target: Erb-b2 receptor tyrosine kinase 2 Alias: c-ERB-2, c-ERB2, CD340, HER-2, HER2, MLN-19, NEU, NGL, p185(erbB2)
ERBB2(HER2/CD340)是ERBB受体酪氨酸激酶家族成员,具有较强的酪氨酸激酶活性,但缺乏已知直接结合配体。HER2可与其他ERBB受体形成二聚体,激活PI3K/AKT、RAS/MAPK等信号通路,调控细胞增殖和存活。 |
产品信息
猴ERBB2 / HER2 / CD340 HEK293过表达细胞系是一种重组细胞系,经工程化改造后可稳定表达细胞表面食蟹猴ERBB2 ,广泛用于机制研究、高通量筛选、药物靶标验证及其他相关领域。
| Host Cell | HEK293 | Gene | ERBB2 / HER2 / CD340 | | Size | >5x10^6 cells per vial | Storage | Liquid nitrogen | | Species | Cynomolgus | Shipment | Dry Ice | | Stability | Validated for at least 10 passages | | Quality Control | Negative for bacteria, yeast, fungi and mycoplasma. | | Applications | Widely used in mechanisms study, high-throughput screening, drug target validation and others. | | Revival | After retrieving the cells from the liquid nitrogen tank, rapidly thaw them in a 37°C water bath. Transfer contents into a tube with pre-warmed media. Centrifuge cells and seed into a 25 cm^2 flask containing pre-warmed media. |

产品验证

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