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人B7-H1 / PD-L1 / CD274 Raji过表达细胞系 Human B7-H1 / PD-L1 / CD274 Raji Cell Line
靶点信息

Target: CD274 molecule Alias: B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1
CD274 molecule(又称 PD-L1,程序性死亡配体 1)是一种在多种肿瘤细胞和免疫细胞表面表达的免疫检查点蛋白,通过与 T 细胞表面的 PD-1 受体结合,负向调控免疫应答,在肿瘤免疫逃逸中发挥关键作用。 |
产品信息
人B7-H1 / PD-L1 / CD274 Raji过表达细胞系是一种重组细胞系,经工程化改造后可在细胞表面稳定表达人 B7-H1 蛋白,广泛用于机制研究、高通量筛选、药物靶标验证及其他相关领域。
| Host Cell | Raji | Gene | B7-H1 / PD-L1 / CD274 | | Size | >5x10^6 cells per vial | Storage | Liquid nitrogen | | Species | Human | Shipment | Dry Ice | | Stability | Validated for at least 10 passages | | Quality Control | Negative for bacteria, yeast, fungi and mycoplasma. | | Applications | Widely used in mechanisms study, high-throughput screening, drug target validation and others. | | Revival | After retrieving the cells from the liquid nitrogen tank, rapidly thaw them in a 37°C water bath. Transfer contents into a tube with pre-warmed media. Centrifuge cells and seed into a 25 cm^2 flask containing pre-warmed media. |

产品验证

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