340855

戊二醛 溶液

Sigma-Aldrich

50 wt. % in H2O

别名：1,5-戊二醛, 五碳双缩醛 溶液

线性分子式：OHC(CH2)3CHO

CAS号：111-30-8

分子量：100.12

Beilstein：605390

MDL编号：MFCD00007025

PubChem化学物质编号：24860868

NACRES：NA.21

属性

蒸汽密度

1.05 (vs air)

质量水平

200

蒸汽压

15 mmHg ( 20 °C)

形式

liquid

浓度

50 wt. % in H2O

颜色

colorless

折射率

n20/D 1.42

mp

-21  °C ((-6 °F))

溶解性

water: soluble

密度

1.106 g/mL at 25 °C

SMILES string

[H]C(CCCC([H])=O)=O

InChI

1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2

InChI key

SXRSQZLOMIGNAQ-UHFFFAOYSA-N

说明

一般描述

Glutaraldehyde (Glutaric dialdehyde, Pentane-1,5-dial) is an aliphatic dialdehyde that can be employed as an effective

 biochemical reagent for various purposes such as a protein crosslinker, enzyme immobilization in microscopy, 

histochemistry, and cytochemistry. It serves as an amine-reactive homobifunctional crosslinker and a cell fixative 

before SDS-PAGE, staining, or electron microscopy, making it suitable for a wide range of morphological studies.

Glutaraldehyde is capable of efficiently crosslinking amine and hydrazine derivatives to proteins and other 

amine-containing polymers. Notably, in certain reactions, biotin hydrazides have been directly coupled to nucleic 

acids using glutaraldehyde, presenting a potential utility in conjugating fluorescent hydrazides and hydroxylamines 

to DNA. In histology studies, Glutaraldehyde is also employed to preserve tissue sections and prepare them for 

closer examination.

应用

戊二醛可用于以下研究:

制备高分辨光学显微镜和电子显微镜研究用的固定液(戊二醛+多聚甲醛+ NaPO4)。

研究山羊抗辣根过氧化物酶与碱性磷酸酶的偶联反应。

组成原代固定剂，用于保护酵母细胞在高锰酸盐固定过程中细胞质特性的恶化。

明胶，聚乙烯醇，和聚庚肽的交联剂。

特点和优势

Versatile and adaptable for wide variety of research applications

Ready-made solution reduces the need for preparation time