维百奥生物现货销售Netrin 1抗体（NP137）

| 产品信息

品名：Netrin 1抗体（NP137）

品牌：Nebulabio

货号： NBR-0330

规格：100ug；1mg；5mg

| 产品描述

NP137 is a "first-in-class" humanized monoclonal antibody targeting the Netrin-1 ligand, a secreted protein recently described as a driver of tumor initiation and progression. NP137 demonstrated anti-tumor activity as a single agent in several pre-clinical models of cancer, including breast and lung cancer.

| 产品属性

针对靶点：Netrin 1

产品外观：Transparent Liquid

分子量：~150kDa

溶解度：Water; PBS, TBS Buffer等

表达系统：CHO Expressed

抗体亚型：Ab. Isotype - IgG

| 基因信息

Gene Name: Netrin 1

Synonyms: NTN1L

Target Description: Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion.

Ensembl: ENSG00000065320 

Uniprot: O95631