Rabies virus (RABV) is an enveloped, single-stranded negative-sense RNA virus belonging to the genus *Lyssavirus* within the family *Rhabdoviridae*. It is the causative agent of rabies and can infect almost all warm-blooded animals, particularly mammals, including humans. RABV exhibits strict neurotropism, and its transmission primarily occurs through contact with the saliva of infected animals via broken skin or mucous membranes. As a globally prevalent zoonotic pathogen, the rabies virus poses a long-term threat to public health. The World Health Organization (WHO) has classified it as a priority infectious disease for prevention and control. Continuous surveillance, research, and preventive measures are crucial for mitigating its impact.

Rabies virus (RABV) belongs to the family *Rhabdoviridae*, and its viral particles exhibit a typical bullet-shaped or rod-like morphology, approximately 180 nm in length and 75 nm in diameter. The viral genome is a non-segmented single-stranded negative-sense RNA, about 12 kb in size, encoding five viral proteins. The entire viral particle consists primarily of the **ribonucleoprotein complex (RNP)**, the **matrix layer**, and the **viral envelope** from the inside out. The RNP contains the genomic RNA and its associated N, P, and L proteins, forming the core for viral transcription and replication. The matrix layer is mainly composed of the M protein, which plays a critical role in connecting the RNP core to the viral envelope, maintaining viral morphology, and facilitating budding. The viral envelope is derived from the host cell membrane and is studded with trimeric spikes of the viral glycoprotein (G protein). These spikes serve as the primary mediators for virus recognition and binding to host cell surface receptors (such as the neural cell adhesion molecule and the p75 neurotrophin receptor), facilitating membrane fusion and cellular entry. Additionally, they are key antigens that induce the production of neutralizing antibodies in the host, making them central targets for vaccine development and diagnostic methods.

Our company provides a comprehensive range of antigens and antibodies for rabies virus.

【Antigens】

【Antibodies】