品名: Tolcapone

货号: N-3007-2

规格: 50 mg

品牌：rPeptide

储存温度：-20℃

序列：N/A

来源：N/A

描述：Catechol O-methyltransferase inhibitor (COMT), inhibiting both brain and peripheral enzymes[1]. Potent inhibitor of alpha-synuclein and beta-amyloid oligomerization and fibrillogenesis protecting against extracellular toxicity[2]. Binds to transthyretin (TTR) with high affinity (21 to 58 nM) and inhibits TTR aggregation in human plasma and prevents TTR-induced cytotoxicity in vitro. Stabilizes TTR in mice and humans in vivo[3]. Inhibits O-methylation of exogenous polyphenols such as EGCG[4]. Cell permeable. Orally bioavailable.

分子量：273.2

纯度：>98%