AlphaThera | AT7003 | oYo-Link® VcMMAF

品名：oYo-Link® VcMMAF

货号：AT7003

规格：100 μg; Bulk

品牌：AlphaThera

产品描述

Site-specifically label your antibody with oYo-Link® VcMMAF for cell killing assays to prototype your ADC candidates.

oYo-Link® VcMMAF is an Antibody-Drug Conjugation reagent allowing for site-specific labeling of VcMMAF (Monomethyl Auristatin F) labels to the heavy-chains of oYo-Link®-compatible antibodies with up to two labels per antibody. VcMMAF is an anti-mitotic agent linked via the lysosomally cleavable dipeptide, valine-citrulline (vc). oYo-Link® limits the attachment of the VcMMAF drugs to the heavy chains of the antibody and therefore ensures that the drug label does not interfere with antibody binding. Furthermore, site-specific labeling limits 1-2 VcMMAF drugs to be attached per antibody, providing precise antibody-drug conjugate ratios.

 Applications：Antibody conjugation reagent for Targeted cell death; Targeted cell death for cancer cells; High-throughput screening with cell killing assays.