AlphaThera | AT7001 | oYo-Link® VcMMAE

品名：oYo-Link® VcMMAE

货号：AT7001

规格：100 μg; Bulk

品牌：AlphaThera

产品描述

Site-specifically label your antibody with oYo-Link® VcMMAE for cell killing assays to prototype your ADC candidates.

oYo-Link® VcMMAE is an Antibody-Drug Conjugation reagent allowing for site-specific labeling of VcMMAE (Monomethyl Auristatin E) labels to the heavy-chains of oYo-Link®-compatible antibodies with up to two labels per antibody. VcMMAE is an anti-mitotic agent linked via the lysosomally cleavable dipeptide, valine-citrulline (vc). oYo-Link® limits the attachment of the VcMMAE drugs to the heavy chains of the antibody and therefore ensures that the drug label does not interfere with antibody binding. Furthermore, site-specific labeling limits attachment of 1-2 VcMMAE drugs per antibody, providing precise antibody-drug conjugate ratios.

 Applications：Antibody conjugation reagent for Targeted cell death; Targeted cell death for cancer cells; High-throughput screening with cell killing assays.